Fractalkine neutralization improves cardiac function after myocardial infarction

Concentrations of the chemokine fractalkine (FKN) are increased in patients with chronic heart failure, and our previous studies show that aged mice lacking the prostaglandin E(2) EP4 receptor subtype (EP4-KO) have increased cardiac FKN, with a phenotype of dilated cardiomyopathy. However, how FKN p...

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Udgivet i:Exp Physiol
Main Authors: Gu, Xiaosong, Xu, Jiang, Yang, Xiao-Ping, Peterson, Edward, Harding, Pamela
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686137/
https://ncbi.nlm.nih.gov/pubmed/25943588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/EP085104
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