Genetic Deletion of 12/15 Lipoxygenase Promotes Effective Resolution of Inflammation Following Myocardial Infarction

12/15 lipoxygenase (LOX) directs inflammation and lipid remodeling. However, the role of 12/15LOX in post-myocardial infarction (MI) left ventricular remodeling is unclear. To determine the role of 12/15LOX, 8-12 week-old C57BL/6J wild-type (WT; n=93) and 12/15LOX(−/−) (n=97) mice were subjected to...

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Bibliografske podrobnosti
izdano v:J Mol Cell Cardiol
Main Authors: Kain, Vasundhara, Ingle, Kevin A., Kabarowski, Janusz, Barnes, Stephen, Limdi, Nita A., Prabhu, Sumanth D., Halade, Ganesh V.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940552/
https://ncbi.nlm.nih.gov/pubmed/29526491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.03.004
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