Interaction of 12/15-lipoxygenase with fatty acids alters the leukocyte kinetics leading to improved postmyocardial infarction healing

The metabolic transformation of fatty acids to form oxylipids using 12/15-lipoxygenase (LOX) can promote either resolving or nonresolving inflammation. However, the mechanism of how 12/15-LOX interacts with polyunsaturated fatty acids (PUFA) in postmyocardial infarction (post-MI) healing is unclear....

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Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Halade, Ganesh V., Kain, Vasundhara, Ingle, Kevin A., Prabhu, Sumanth D.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538863/
https://ncbi.nlm.nih.gov/pubmed/28411230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00040.2017
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