Interaction of 12/15-lipoxygenase with fatty acids alters the leukocyte kinetics leading to improved postmyocardial infarction healing

The metabolic transformation of fatty acids to form oxylipids using 12/15-lipoxygenase (LOX) can promote either resolving or nonresolving inflammation. However, the mechanism of how 12/15-LOX interacts with polyunsaturated fatty acids (PUFA) in postmyocardial infarction (post-MI) healing is unclear....

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Veröffentlicht in:Am J Physiol Heart Circ Physiol
Hauptverfasser: Halade, Ganesh V., Kain, Vasundhara, Ingle, Kevin A., Prabhu, Sumanth D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538863/
https://ncbi.nlm.nih.gov/pubmed/28411230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00040.2017
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