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Activation of EP4 receptor limits transition of acute to chronic heart failure in lipoxygenase deficient mice

Aim: Immune responsive 12/15 lipoxygenase (12/15LOX)-orchestrate biosynthesis of essential inflammation-resolution mediators during acute inflammatory response in post-myocardial infarction (MI). Lack of 12/15LOX dampens proinflammatory mediator 12-(S)-hydroxyeicosatetraenoic acid (12-(S)-HETE), imp...

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Bibliografiska uppgifter
I publikationen:Theranostics
Huvudupphovsmän: Kain, Vasundhara, Ingle, Kevin A., Rajasekaran, Namakkal S., Halade, Ganesh V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ivyspring International Publisher 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806484/
https://ncbi.nlm.nih.gov/pubmed/33456570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.51183
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