Inflammasome Independent Leukotriene-B(4) Production Drives Crystalline Silica Induced Sterile Inflammation

Silicosis is a lung inflammatory disease caused by chronic exposure to crystalline silica (CS). Leukotriene B(4) (LTB(4)) plays an important role in neutrophilic inflammation that drives silicosis and promotes lung cancer. Here, we examined the mechanisms involved in CS-induced inflammatory pathways...

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Vydáno v:J Immunol
Hlavní autoři: Hegde, Bindu, Bodduluri, Sobha R., Satpathy, Shuchismita R., Alghsham, Ruqaih S., Jala, Venkatakrishna R., Uriarte, Silvia M., Chung, Dong-Hoon, Lawrenz, Matthew B., Haribabu, Bodduluri
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940517/
https://ncbi.nlm.nih.gov/pubmed/29610142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701504
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