Crystalline silica-induced leukotrieneB(4)-dependent inflammation promotes lung tumor growth

Chronic exposure to crystalline silica (CS) causes silicosis, an irreversible lung inflammatory disease that may eventually lead to lung cancer. In this study, we demonstrate that in K-ras(LA1) mice, CS exposure markedly enhances the lung tumor burden and genetic deletion of leukotriene B(4) recepto...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Satpathy, Shuchismita R., Jala, Venkatakrishna R., Bodduluri, Sobha R., Krishnan, Elangovan, Hegde, Bindu, Hoyle, Gary, Fraig, Mostafa, Luster, Andrew D., Haribabu, Bodduluri
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418220/
https://ncbi.nlm.nih.gov/pubmed/25923988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8064
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