Inflammasome Independent Leukotriene-B(4) Production Drives Crystalline Silica Induced Sterile Inflammation

Silicosis is a lung inflammatory disease caused by chronic exposure to crystalline silica (CS). Leukotriene B(4) (LTB(4)) plays an important role in neutrophilic inflammation that drives silicosis and promotes lung cancer. Here, we examined the mechanisms involved in CS-induced inflammatory pathways...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hegde, Bindu, Bodduluri, Sobha R., Satpathy, Shuchismita R., Alghsham, Ruqaih S., Jala, Venkatakrishna R., Uriarte, Silvia M., Chung, Dong-Hoon, Lawrenz, Matthew B., Haribabu, Bodduluri
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940517/
https://ncbi.nlm.nih.gov/pubmed/29610142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701504
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