Inflammasome Independent Leukotriene-B(4) Production Drives Crystalline Silica Induced Sterile Inflammation

Silicosis is a lung inflammatory disease caused by chronic exposure to crystalline silica (CS). Leukotriene B(4) (LTB(4)) plays an important role in neutrophilic inflammation that drives silicosis and promotes lung cancer. Here, we examined the mechanisms involved in CS-induced inflammatory pathways...

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Publicado en:J Immunol
Autores principales: Hegde, Bindu, Bodduluri, Sobha R., Satpathy, Shuchismita R., Alghsham, Ruqaih S., Jala, Venkatakrishna R., Uriarte, Silvia M., Chung, Dong-Hoon, Lawrenz, Matthew B., Haribabu, Bodduluri
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940517/
https://ncbi.nlm.nih.gov/pubmed/29610142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701504
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