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Epigenetic plasticity and the hallmarks of cancer

Chromatin and associated epigenetic mechanisms stabilize gene expression and cellular states, while also facilitating appropriate responses to developmental or environmental cues. Genetic, environmental or metabolic insults can induce overly restrictive or overly permissive epigenetic landscapes tha...

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Detalles Bibliográficos
Publicado en:Science
Main Authors: Flavahan, William A., Gaskell, Elizabeth, Bernstein, Bradley E.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940341/
https://ncbi.nlm.nih.gov/pubmed/28729483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aal2380
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