Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A

Triple negative breast cancer (TNBC) is characterized by poor prognosis and a DNA hypomethylation profile. Withaferin A (WA) is a plant derived steroidal lactone which holds promise as a therapeutic agent for treatment of breast cancer (BC). We determined genome-wide DNA methylation changes in weakl...

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發表在:Oncotarget
Main Authors: vel Szic, Katarzyna Szarc, Declerck, Ken, Crans, René A.J, Diddens, Jolien, Scherf, David B., Gerhäuser, Clarissa, Berghe, Wim Vanden
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522326/
https://ncbi.nlm.nih.gov/pubmed/28467815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17107
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