Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A

Triple negative breast cancer (TNBC) is characterized by poor prognosis and a DNA hypomethylation profile. Withaferin A (WA) is a plant derived steroidal lactone which holds promise as a therapeutic agent for treatment of breast cancer (BC). We determined genome-wide DNA methylation changes in weakl...

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Publicat a:Oncotarget
Autors principals: vel Szic, Katarzyna Szarc, Declerck, Ken, Crans, René A.J, Diddens, Jolien, Scherf, David B., Gerhäuser, Clarissa, Berghe, Wim Vanden
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522326/
https://ncbi.nlm.nih.gov/pubmed/28467815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17107
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