Defect-Facilitated Buckling in Supercoiled Double-Helix DNA

We present a statistical-mechanical model for stretched twisted double-helix DNA, where thermal fluctuations are treated explicitly from a Hamiltonian without using any scaling hypotheses. Our model applied to defect-free supercoiled DNA describes coexistence of multiple plectoneme domains in long D...

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Udgivet i:Phys Rev E
Main Authors: Brahmachari, Sumitabha, Dittmore, Andrew, Takagi, Yasuharu, Neuman, Keir C., Marko, John F.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940003/
https://ncbi.nlm.nih.gov/pubmed/29548184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevE.97.022416
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