Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

Epithelial to mesenchymal transition (EMT) in cancer cells has been associated with metastasis, sternness, and resistance to therapy. Some tumors undergo EMT while others do not, which may reflect intrinsic properties of their cell of origin. However, this possibility is largely unexplored. By targe...

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Publicat a:Cell Stem Cell
Autors principals: Latil, Mathilde, Nassar, Dany, Beck, Benjamin, Boumahdi, Soufiane, Wang, Li, Brisebarre, Audrey, Dubois, Christine, Nkusi, Erwin, Lenglez, Sandrine, Checinska, Agnieszka, Drubbel, Alizée Vercauteren, Devos, Michael, Declercq, Wim, Yi, Rui, Blanpain, Cedric
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939571/
https://ncbi.nlm.nih.gov/pubmed/27889319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.018
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