Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

Epithelial to mesenchymal transition (EMT) in cancer cells has been associated with metastasis, sternness, and resistance to therapy. Some tumors undergo EMT while others do not, which may reflect intrinsic properties of their cell of origin. However, this possibility is largely unexplored. By targe...

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Bibliographic Details
Published in:Cell Stem Cell
Main Authors: Latil, Mathilde, Nassar, Dany, Beck, Benjamin, Boumahdi, Soufiane, Wang, Li, Brisebarre, Audrey, Dubois, Christine, Nkusi, Erwin, Lenglez, Sandrine, Checinska, Agnieszka, Drubbel, Alizée Vercauteren, Devos, Michael, Declercq, Wim, Yi, Rui, Blanpain, Cedric
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939571/
https://ncbi.nlm.nih.gov/pubmed/27889319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.018
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