Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

Epithelial to mesenchymal transition (EMT) in cancer cells has been associated with metastasis, sternness, and resistance to therapy. Some tumors undergo EMT while others do not, which may reflect intrinsic properties of their cell of origin. However, this possibility is largely unexplored. By targe...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Latil, Mathilde, Nassar, Dany, Beck, Benjamin, Boumahdi, Soufiane, Wang, Li, Brisebarre, Audrey, Dubois, Christine, Nkusi, Erwin, Lenglez, Sandrine, Checinska, Agnieszka, Drubbel, Alizée Vercauteren, Devos, Michael, Declercq, Wim, Yi, Rui, Blanpain, Cedric
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939571/
https://ncbi.nlm.nih.gov/pubmed/27889319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.018
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