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Tunable cytotoxic aptamer–drug conjugates for the treatment of prostate cancer
Therapies that can eliminate both local and metastatic prostate tumor lesions while sparing normal organ tissue are desperately needed. With the goal of developing an improved drug-targeting strategy, we turned to a new class of targeted anticancer therapeutics: aptamers conjugated to highly toxic c...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5939073/ https://ncbi.nlm.nih.gov/pubmed/29666232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717705115 |
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