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Improved Synthesis and In Vitro Evaluation of an Aptamer Ribosomal Toxin Conjugate
Delivery of toxins, such as the ricin A chain, Pseudomonas exotoxin, and gelonin, using antibodies has had some success in inducing specific toxicity in cancer treatments. However, these antibody-toxin conjugates, called immunotoxins, can be bulky, difficult to express, and may induce an immune resp...
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| Publicado no: | Nucleic Acid Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932783/ https://ncbi.nlm.nih.gov/pubmed/27228412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2015.0599 |
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