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Tunable cytotoxic aptamer–drug conjugates for the treatment of prostate cancer

Therapies that can eliminate both local and metastatic prostate tumor lesions while sparing normal organ tissue are desperately needed. With the goal of developing an improved drug-targeting strategy, we turned to a new class of targeted anticancer therapeutics: aptamers conjugated to highly toxic c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Powell Gray, Bethany, Kelly, Linsley, Ahrens, Douglas P., Barry, Ashley P., Kratschmer, Christina, Levy, Matthew, Sullenger, Bruce A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939073/
https://ncbi.nlm.nih.gov/pubmed/29666232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717705115
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