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IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils

Binding of allergen-specific IgE to its primary receptor FcεRI on basophils and mast cells represents a central event in the development of allergic diseases. The high-affinity interaction between IgE and FcεRI results in permanent sensitization of these allergic effector cells and critically regula...

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書目詳細資料
發表在:Cell Death Dis
Main Authors: Zellweger, Fabian, Buschor, Patrick, Hobi, Gabriel, Brigger, Daniel, Dahinden, Clemens Andreas, Villiger, Peter Matthias, Eggel, Alexander
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938712/
https://ncbi.nlm.nih.gov/pubmed/29724998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0526-9
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