Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia

The AML1-ETO fusion protein (A/E), which results from the t(8;21) translocation, is considered to be a leukemia-initiating event. Identifying the mechanisms underlying the oncogenic activity of A/E remains a major challenge. In this study, we identified a specific down-regulation of brain acid-solub...

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Publicado en:Exp Mol Med
Main Authors: Zhou, Lei, Fu, Lin, Lv, Na, Liu, Jing, Li, Yan, Chen, Xiaosu, Xu, Qingyu, Chen, Guofeng, Pang, Baoxu, Wang, Lili, Li, Yonghui, Zhang, Xiaodong, Yu, Li
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938046/
https://ncbi.nlm.nih.gov/pubmed/29674693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0067-4
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