Epigenetic Silencing of Eyes Absent 4 Gene by Acute Myeloid Leukemia 1-Eight-twenty-one Oncoprotein Contributes to Leukemogenesis in t(8;21) Acute Myeloid Leukemia

BACKGROUND: The acute myeloid leukemia 1 (AML1)-eight-twenty-one (ETO) fusion protein generated by the t(8;21)(q22;q22) translocation is considered to display a crucial role in leukemogenesis in AML. By focusing on the anti-leukemia effects of eyes absent 4 (EYA4) gene on AML cells, we investigated...

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Detalhes bibliográficos
Publicado no:Chin Med J (Engl)
Main Authors: Huang, Sai, Jiang, Meng-Meng, Chen, Guo-Feng, Qian, Kun, Gao, Hong-Hao, Guan, Wei, Shi, Jin-Long, Liu, An-Qi, Liu, Jing, Wang, Bian-Hong, Li, Yong-Hui, Yu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894048/
https://ncbi.nlm.nih.gov/pubmed/27231175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0366-6999.182838
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