S-nitrosylation of transglutaminase 2 impairs fatty acid-stimulated contraction in hypertensive cardiomyocytes

The myocardium in hypertensive heart exhibits decreased fatty acid utilization and contractile dysfunction, leading to cardiac failure. However, the causal relationship between metabolic remodeling and cardiomyocyte contractility remains unestablished. Transglutaminase 2 (TG2) has been known to prom...

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Veröffentlicht in:Exp Mol Med
Hauptverfasser: Jeong, Eui Man, Jin, Chun Zi, Jang, Ji Hyun, Zhao, Zai Hao, Jin, Chun Li, Lee, Jin Hang, Lee, Ki Baek, Kim, Sung Joon, Kim, In-Gyu, Zhang, Yin Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938015/
https://ncbi.nlm.nih.gov/pubmed/29622788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-017-0021-x
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