S-nitrosylation of transglutaminase 2 impairs fatty acid-stimulated contraction in hypertensive cardiomyocytes

The myocardium in hypertensive heart exhibits decreased fatty acid utilization and contractile dysfunction, leading to cardiac failure. However, the causal relationship between metabolic remodeling and cardiomyocyte contractility remains unestablished. Transglutaminase 2 (TG2) has been known to prom...

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Publicado no:Exp Mol Med
Principais autores: Jeong, Eui Man, Jin, Chun Zi, Jang, Ji Hyun, Zhao, Zai Hao, Jin, Chun Li, Lee, Jin Hang, Lee, Ki Baek, Kim, Sung Joon, Kim, In-Gyu, Zhang, Yin Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938015/
https://ncbi.nlm.nih.gov/pubmed/29622788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-017-0021-x
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