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Long-term correction of hemophilia A mice following lentiviral mediated delivery of an optimized canine factor VIII gene
Current therapies for hemophilia A include frequent prophylactic or on-demand intravenous factor treatments which are costly, inconvenient and may lead to inhibitor formation. Viral vector delivery of factor VIII (FVIII) cDNA has the potential to alleviate the debilitating clotting defects. Lentivir...
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| Publicado no: | Gene Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937993/ https://ncbi.nlm.nih.gov/pubmed/28905885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2017.67 |
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