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The Relation between α-Helical Conformation and Amyloidogenicity
Amyloid fibrils are stable aggregates of misfolded proteins and polypeptides that are insoluble and resistant to protease activity. Abnormal formation of amyloid fibrils in vivo may lead to neurodegenerative disorders and other systemic amyloidosis, such as Alzheimer’s, Parkinson’s, and atherosclero...
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| Pubblicato in: | Biophys J |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937719/ https://ncbi.nlm.nih.gov/pubmed/29653837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.03.019 |
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