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O-GlcNAc transferase recognizes protein substrates using an asparagine ladder in the TPR superhelix
The essential mammalian enzyme O-GlcNAc Transferase (OGT) is uniquely responsible for transferring N-acetylglucosamine to over a thousand nuclear and cytoplasmic proteins, yet there is no known consensus sequence and it remains unclear how OGT recognizes its substrates. To address this question, we...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937710/ https://ncbi.nlm.nih.gov/pubmed/29485866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b13546 |
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