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Organocatalytic Asymmetric Synthesis of α-Oxetanyl and α-Azetidinyl Tertiary Alkyl Fluorides and Chlorides
Asymmetric thiourea and squaramide catalysis provides access to synthetically versatile α-oxetanyl- and α-azetidinyl alkyl halides exhibiting a tetrasubstituted chiral carbon center with high yields and enantioselectivities. The products are readily transformed with negligible erosion of enantiopuri...
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| Publicado no: | Org Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937693/ https://ncbi.nlm.nih.gov/pubmed/29360370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b00039 |
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