Comparison of the effects of deferasirox, deferoxamine, and combination of deferasirox and deferoxamine on an aplastic anemia mouse model complicated with iron overload

BACKGROUND AND AIM: Iron overload is commonly observed during the course of aplastic anemia (AA), which is believed to aggravate hematopoiesis, cause multiple organ dysfunction, lead to disease progression, and impair quality of life. Deferasirox (DFX) and deferoxamine (DFO) are among the most commo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Des Devel Ther
Prif Awduron: Wu, Dijiong, Wen, Xiaowen, Liu, Wenbin, Hu, Huijin, Ye, Baodong, Zhou, Yuhong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2018
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937503/
https://ncbi.nlm.nih.gov/pubmed/29760547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S161086
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