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Effects of deferasirox-deferoxamine on myocardial and liver iron in patients with severe transfusional iron overload

Deferasirox (DFX) monotherapy is effective for reducing myocardial and liver iron concentrations (LIC), although some patients may require intensive chelation for a limited duration. HYPERION, an open-label single-arm prospective phase 2 study, evaluated combination DFX-deferoxamine (DFO) in patient...

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Bibliografiska uppgifter
I publikationen:Blood
Huvudupphovsmän: Aydinok, Yesim, Kattamis, Antonis, Cappellini, M. Domenica, El-Beshlawy, Amal, Origa, Raffaella, Elalfy, Mohsen, Kilinç, Yurdanur, Perrotta, Silverio, Karakas, Zeynep, Viprakasit, Vip, Habr, Dany, Constantinovici, Niculae, Shen, Junwu, Porter, John B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490296/
https://ncbi.nlm.nih.gov/pubmed/25934475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-586677
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