Oral treatment with plecanatide or dolcanatide attenuates visceral hypersensitivity via activation of guanylate cyclase-C in rat models

AIM: To investigate the effects of plecanatide and dolcanatide on maintenance of paracellular permeability, integrity of tight junctions and on suppression of visceral hypersensitivity. METHODS: Transport of fluorescein isothiocyanate (FITC)-dextran was measured to assess permeability across cell mo...

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Dades bibliogràfiques
Publicat a:World J Gastroenterol
Autors principals: Boulete, Illona-Marie, Thadi, Anusha, Beaufrand, Catherine, Patwa, Viren, Joshi, Apoorva, Foss, John A, Eddy, E Priya, Eutamene, Helene, Palejwala, Vaseem A, Theodorou, Vassilia, Shailubhai, Kunwar
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2018
Matèries:
Basic Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937206/
https://ncbi.nlm.nih.gov/pubmed/29740204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v24.i17.1888
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