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Reexamining Dis/Similarity-Based Tests for Rare-Variant Association with Case-Control Samples

A properly designed distance-based measure can capture informative genetic differences among individuals with different phenotypes and can be used to detect variants responsible for the phenotypes. To detect associated variants, various tests have been designed to contrast genetic dissimilarity or s...

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Bibliografische gegevens
Gepubliceerd in:Genetics
Hoofdauteurs: Wang, Charlotte, Tzeng, Jung-Ying, Wu, Pei-Zhen, Preisig, Martin, Hsiao, Chuhsing Kate
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937191/
https://ncbi.nlm.nih.gov/pubmed/29545466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300769
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