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Reexamining Dis/Similarity-Based Tests for Rare-Variant Association with Case-Control Samples

A properly designed distance-based measure can capture informative genetic differences among individuals with different phenotypes and can be used to detect variants responsible for the phenotypes. To detect associated variants, various tests have been designed to contrast genetic dissimilarity or s...

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Détails bibliographiques
Publié dans:Genetics
Auteurs principaux: Wang, Charlotte, Tzeng, Jung-Ying, Wu, Pei-Zhen, Preisig, Martin, Hsiao, Chuhsing Kate
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937191/
https://ncbi.nlm.nih.gov/pubmed/29545466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300769
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