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Decarboxylative Annulation of α-Amino Acids with β-Ketoaldehydes

Indolizidine and quinolizidine derivatives are readily assembled from L-proline or (±)-pipecolic acid and β-ketoaldehydes via a decarboxylative annulation process. These reactions are promoted by acetic acid and involve azomethine ylides as reactive intermediates.

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Bibliografische gegevens
Gepubliceerd in:Org Lett
Hoofdauteurs: Paul, Anirudra, Thimmegowda, N. R., Cruz, Thiago Galani, Seidel, Daniel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937137/
https://ncbi.nlm.nih.gov/pubmed/29328663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b03721
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