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Decarboxylative Annulation of α-Amino Acids with β-Ketoaldehydes
Indolizidine and quinolizidine derivatives are readily assembled from L-proline or (±)-pipecolic acid and β-ketoaldehydes via a decarboxylative annulation process. These reactions are promoted by acetic acid and involve azomethine ylides as reactive intermediates.
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| Published in: | Org Lett |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937137/ https://ncbi.nlm.nih.gov/pubmed/29328663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b03721 |
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