Emerging Concepts in Immune Thrombocytopenia

Immune thrombocytopenia (ITP) is an autoimmune disease defined by low platelet counts which presents with an increased bleeding risk. Several genetic risk factors (e.g., polymorphisms in immunity-related genes) predispose to ITP. Autoantibodies and cytotoxic CD8(+) T cells (Tc) mediate the anti-plat...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Swinkels, Maurice, Rijkers, Maaike, Voorberg, Jan, Vidarsson, Gestur, Leebeek, Frank W. G., Jansen, A. J. Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937051/
https://ncbi.nlm.nih.gov/pubmed/29760702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00880
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