A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation

HLA antibodies are associated with refractoriness to platelet transfusion, leading to rapid platelet clearance, sometimes coinciding with clinical side effects such as fever and chills. The presence of HLA antibodies is not always manifested by clinical symptoms. It is currently unclear why refracto...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Rijkers, Maaike, Saris, Anno, Heidt, Sebastiaan, Mulder, Arend, Porcelijn, Leendert, Claas, Frans H.J., Bierings, Ruben, Leebeek, Frank W.G., Jansen, A.J. Gerard, Vidarsson, Gestur, Voorberg, Jan, de Haas, Masja
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165798/
https://ncbi.nlm.nih.gov/pubmed/29858387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.189365
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