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Structure of Transmembrane Helix 8 and Possible Membrane Defects in CFTR
The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel that regulates the flow of anions across epithelia. Mutations in CFTR cause cystic fibrosis. CFTR belongs to the ATP-binding cassette transporter superfamily, and gating is controlled by phosphorylation and ATP binding...
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| Udgivet i: | Biophys J |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5936993/ https://ncbi.nlm.nih.gov/pubmed/29694855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.03.003 |
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