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Structure of Transmembrane Helix 8 and Possible Membrane Defects in CFTR

The cystic fibrosis transmembrane conductance regulator (CFTR) is an ion channel that regulates the flow of anions across epithelia. Mutations in CFTR cause cystic fibrosis. CFTR belongs to the ATP-binding cassette transporter superfamily, and gating is controlled by phosphorylation and ATP binding...

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Bibliografski detalji
Izdano u:Biophys J
Glavni autori: Corradi, Valentina, Gu, Ruo-Xu, Vergani, Paola, Tieleman, D. Peter
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936993/
https://ncbi.nlm.nih.gov/pubmed/29694855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.03.003
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