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Histone deacetylase–mediated regulation of endolysosomal pH
The pH of the endolysosomal system is tightly regulated by a balance of proton pump and leak mechanisms that are critical for storage, recycling, turnover, and signaling functions in the cell. Dysregulation of endolysosomal pH has been linked to aging, amyloidogenesis, synaptic dysfunction, and vari...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5936830/ https://ncbi.nlm.nih.gov/pubmed/29567836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002025 |
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