Histone Acetylation Regulates Intracellular pH

Differences in global levels of histone acetylation occur in normal and cancer cells, although the reason why cells regulate these levels has been unclear. Here we demonstrate a role for histone acetylation in regulating intracellular pH (pH(i)). As pH(i) decreases, histones are globally deacetylate...

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Hauptverfasser: McBrian, Matthew A., Behbahan, Iman Saramipoor, Ferrari, Roberto, Su, Trent, Huang, Ta-Wei, Li, Kunwu, Hong, Candice S., Christofk, Heather R., Vogelauer, Maria, Seligson, David B., Kurdistani, Siavash K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893119/
https://ncbi.nlm.nih.gov/pubmed/23201122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.10.025
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