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The HUS box is required for allosteric regulation of the Sec7 Arf-GEF
The Golgi complex is the central membrane and protein-sorting station in eukaryotic cells. Activation of Arf (ADP-ribosylation factor) GTPases is essential for vesicle formation via recruitment of cargo adaptors and coat proteins necessary for Golgi trafficking. Arf activation is spatially and tempo...
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| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5936818/ https://ncbi.nlm.nih.gov/pubmed/29514977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001318 |
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