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The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase
The Golgi complex is the central sorting compartment of eukaryotic cells. Arf guanine nucleotide exchange factors (Arf-GEFs) regulate virtually all traffic through the Golgi by activating Arf GTPase trafficking pathways. The Golgi Arf-GEFs contain multiple autoregulatory domains, but the precise mec...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764562/ https://ncbi.nlm.nih.gov/pubmed/26765562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12411 |
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