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The Sec7 Arf-GEF is recruited to the trans-Golgi network by positive feedback

Arf GTPases are key regulators of both retrograde and anterograde traffic at the Golgi complex. The Golgi-localized Arf activators, Arf-GEFs (guanine exchange factor) of the BIG/GBF family, are poorly understood in terms of both their regulatory and localization mechanisms. We have performed a detai...

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Autori principali: Richardson, Brian C., McDonold, Caitlin M., Fromme, J. Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331996/
https://ncbi.nlm.nih.gov/pubmed/22516198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.02.006
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