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Biased Signalling: From Simple Switches to Allosteric Microprocessors
G protein-coupled receptors (GPCRs) are the largest class of receptors in the human genome and one of the most common drug targets. It is now well-established that GPCRs can signal through multiple transducers, including heterotrimeric G proteins, G protein receptor kinases and βarrestins. While the...
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| Gepubliceerd in: | Nat Rev Drug Discov |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5936084/ https://ncbi.nlm.nih.gov/pubmed/29302067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2017.229 |
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