Physiologically based pharmacokinetic modeling of nanoceria systemic distribution in rats suggests dose- and route-dependent biokinetics

BACKGROUND: Cerium dioxide nanoparticles (nanoceria) are increasingly being used in a variety of products as catalysts, coatings, and polishing agents. Furthermore, their antioxidant properties make nanoceria potential candidates for biomedical applications. To predict and avoid toxicity, informatio...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Carlander, Ulrika, Moto, Tshepo Paulsen, Desalegn, Anteneh Assefa, Yokel, Robert A, Johanson, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936012/
https://ncbi.nlm.nih.gov/pubmed/29750034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S157210
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