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Effects of Dose and Route of Administration on Pharmacokinetics of (±)-3,4-Methylenedioxymethamphetamine in the Rat

Based on animal data, there is speculation that (±)-3,4-methylenedioxymethamphetamine (MDMA) is neurotoxic to humans. Extrapolation of MDMA findings from animals to humans requires assessment of pharmacokinetics in various species, and low-dose administration data from rats are lacking. In this stud...

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Главные авторы: Baumann, Michael H., Zolkowska, Dorota, Kim, Insook, Scheidweiler, Karl B., Rothman, Richard B., Huestis, Marilyn A.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774984/
https://ncbi.nlm.nih.gov/pubmed/19679675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.109.028506
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