Response to Comments on “The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport”

Baranovskiy et al. and Pellegrini argue that, based on structural data, the path for charge transfer through the [4Fe4S] domain of primase is not feasible. Our manuscript presents electrochemical data directly showing charge transport through DNA to the [4Fe4S] cluster of a primase p58C construct an...

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Enregistré dans:
Détails bibliographiques
Publié dans:Science
Auteurs principaux: O’Brien, Elizabeth, Holt, Marilyn E., Thompson, Matthew K., Salay, Lauren E., Ehlinger, Aaron C., Chazin, Walter J., Barton, Jacqueline K.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935490/
https://ncbi.nlm.nih.gov/pubmed/28729485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan2762
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