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Comment on “The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport”
O’Brien et al. (Research Articles, 24 February 2017, eaag1789) proposed a novel mechanism of primase function based on redox activity of the iron-sulfur cluster buried inside the C-terminal domain of the large primase subunit (p58C). Serious problems in the experimental design and data interpretatio...
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| Publicado en: | Science |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741086/ https://ncbi.nlm.nih.gov/pubmed/28729484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan2396 |
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