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Comment on “The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport”

O’Brien et al. (Research Articles, 24 February 2017, eaag1789) proposed a novel mechanism of primase function based on redox activity of the iron-sulfur cluster buried inside the C-terminal domain of the large primase subunit (p58C). Serious problems in the experimental design and data interpretatio...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Baranovskiy, Andrey G., Babayeva, Nigar D., Zhang, Yinbo, Blanco, Luis, Pavlov, Youri I., Tahirov, Tahir H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741086/
https://ncbi.nlm.nih.gov/pubmed/28729484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan2396
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