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Therapeutic potential of chemically modified siRNA: Recent trends
Small Interfering RNAs (siRNAs) are one of the valuable tools to investigate the functions of genes, and are also used for gene silencing. It has a wide scope in drug discovery through in vivo target validation. siRNA therapeutics are not optimal drug-like molecules due to poor bioavailability, immu...
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| 出版年: | Chem Biol Drug Des |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5935465/ https://ncbi.nlm.nih.gov/pubmed/28378934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12993 |
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