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Comparison of algorithms for the detection of cancer-drivers at sub-gene resolution

Understanding genetic events that lead to cancer initiation and progression remains one of the biggest challenges in cancer biology. Traditionally most algorithms for cancer driver identification look for genes that have more mutations than expected from the average background mutation rate. However...

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Vydáno v:Nat Methods
Hlavní autoři: Porta-Pardo, Eduard, Kamburov, Atanas, Tamborero, David, Pons, Tirso, Grases, Daniela, Valencia, Alfonso, Lopez-Bigas, Nuria, Getz, Gad, Godzik, Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935266/
https://ncbi.nlm.nih.gov/pubmed/28714987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4364
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