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Comparison of algorithms for the detection of cancer-drivers at sub-gene resolution

Understanding genetic events that lead to cancer initiation and progression remains one of the biggest challenges in cancer biology. Traditionally most algorithms for cancer driver identification look for genes that have more mutations than expected from the average background mutation rate. However...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Porta-Pardo, Eduard, Kamburov, Atanas, Tamborero, David, Pons, Tirso, Grases, Daniela, Valencia, Alfonso, Lopez-Bigas, Nuria, Getz, Gad, Godzik, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935266/
https://ncbi.nlm.nih.gov/pubmed/28714987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4364
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