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Mutation drivers of immunological responses to cancer

In cancer immunology, somatic missense mutations have been mostly studied regarding their role in the generation of neoantigens. However, growing evidence suggests that mutations in certain genes, such as CASP8 or TP53, influence the immune response against a tumor by other mechanisms. Identifying t...

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Detalles Bibliográficos
Publicado en:Cancer Immunol Res
Main Authors: Porta-Pardo, Eduard, Godzik, Adam
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886853/
https://ncbi.nlm.nih.gov/pubmed/27401919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0233
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