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Mutation drivers of immunological responses to cancer

In cancer immunology, somatic missense mutations have been mostly studied regarding their role in the generation of neoantigens. However, growing evidence suggests that mutations in certain genes, such as CASP8 or TP53, influence the immune response against a tumor by other mechanisms. Identifying t...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Porta-Pardo, Eduard, Godzik, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886853/
https://ncbi.nlm.nih.gov/pubmed/27401919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0233
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