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Mutation drivers of immunological responses to cancer

In cancer immunology, somatic missense mutations have been mostly studied regarding their role in the generation of neoantigens. However, growing evidence suggests that mutations in certain genes, such as CASP8 or TP53, influence the immune response against a tumor by other mechanisms. Identifying t...

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Bibliographic Details
Published in:Cancer Immunol Res
Main Authors: Porta-Pardo, Eduard, Godzik, Adam
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886853/
https://ncbi.nlm.nih.gov/pubmed/27401919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0233
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